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I have not come across much of the stigma surrounding ketogenic diets. I think scientists are much more open-minded than doctors. It was very easy for me to find tutors interested in low carb and high fat diets.
– Bryan Barksdale
We’ve already seen a great deal of scientific evidence supporting ketogenic, high-fat, and high-fat diets. But the evidence doesn’t stop there; Very good scientific research is being done on other common diseases, but it is not so definitive.
The effects of ketosis conditions discussed in this article are not long-term studies; All of the proposed studies lasted a year or less, but they appear to respond quite well to ketogenic nutrition therapy and have shown great promise in future controlled clinical trials on when it can get financing.
Alzheimer’s disease (AD), Parkinson’s disease, and dementia
The increased availability of ketones has been shown to improve cognitive function in patients with mild Alzheimer’s disease. The science is so compelling that the FDA approved a medical food that increases the availability of ketones as a treatment for Alzheimer’s. In one study, a ketogenic diet provided more improvements in functionality for Parkinson’s patients than pharmaceutical interventions.
– Dr. David Perlmutter
The human brain needs fat and cholesterol to function properly and can be fed glucose or ketones. After a ketone adjustment, after consuming a low-carbohydrate, high-fat diet, the brain draws most of its energy from the body.
This becomes an important factor when we begin to study brain diseases such as Alzheimer’s, Parkinson’s, and dementia.
We know that being in a state of ketosis reduces chronic levels of inflammation, provides the brain with a wonderful source of fuel, and significantly reduces the production of insulin involved in the development of these neurological diseases.
Alzheimer’s disease, now referred to in research circles as “type 3 diabetes,” is a progressive dementia that causes memory and function loss due to a lack of insulin sensitivity in the brain. Unfortunately, there is no good treatment for this. Just as insulin resistance leads to the development of type 2 diabetes, so does brain insulin resistance to the development of Alzheimer’s disease.
When the brain cannot receive its main source of fuel (glucose), signs of mental decline begin.
The human brain functions effectively in the state of ketosis, and researchers are increasingly examining early cognitive decline as a viable means of correcting, and perhaps preventing or reversing, dementia, as well as Alzheimer’s.
Neurologists know very well that dietary fat free from sugar and starch is tremendously stabilized in the human brain and nervous system, dramatically improving blood flow to the brain by 39 percent!
– Nora Gedgaudas
There is a strong theoretical basis for placing Alzheimer’s patients on a low-fat and low-fat diet as a means of further preventing the progression of AD because it is linked to the development of this inflammation caused by gluten, carbohydrates and high blood glucose levels. disease. Also, ketone is easily absorbed into the brain by the body when there is no glucose as an alternative fuel source.
In fact, the idea of delivering ketones to the brain to treat dementia-related conditions instead of glucose has led to the development of a new medical food called Axona.
A randomized controlled clinical trial has shown that an increase in ketone levels in the blood for 90 days has led to a slight improvement in brain function in patients with dementia, which, without treatment, almost always leads to Alzheimer’s or Parkinson’s. Dr. Mary Newport knows a thing or two about Alzheimer’s disease.
Her husband, Steve, was diagnosed with an early diagnosis of Alzheimer’s at the age of fifty, and quickly became frustrated at the lack of meaningful therapies to help slow its progression, let alone reverse the damage already done.
When Dr. Newport began feeding large amounts of coconut and MCT oils while eliminating carbohydrate-based foods from bread, rice, and pasta, he began to “climb the Alzheimer’s abyss.” Share the details of Steve’s miraculous change in his book Alzheimer’s Disease: What if there was a cure?
Dr. Newport’s experience is not isolated. He has informed hundreds of caregivers of Alzheimer’s, Parkinson’s and dementia patients that they have found different levels of improvement following the same protocol as him . Some of these patients have been stable for four years because they have been successful in ketosis.
Thanks to a grant from a private foundation, they are already conducting a clinical study at the University of South Florida to study the effect of ketosis caused by coconut oil on Alzheimer’s disease. The results of this study may contribute to the efficacy of the ketogenic diet in treating Alzheimer’s disease. The evidence that the brain prefers ketones to the body seems quite attractive to me.
Also, when ketones are involved in reducing oxidative stress in the body, it begins to explain some of the significant improvements we see in health when people follow a ketogenic diet.
– Dr. Jay Wortman
The mechanisms of Parkinson’s disease are very similar to those of Alzheimer’s disease, so it is theorized that diet is an effective treatment for Parkinson’s disease.
In an uncontrolled clinical study published in the journal Neurology on February 22, 2005, five patients on a 28-day diet followed a diet that was very low in carbohydrates (2% calories) and very high in fat (90% calories). measured for twenty-eight days.
Her balance improved, her shaking and shaking stopped, and overall her mood was much happier. The brain loves ketones, mainly due to Alzheimer’s or Parkinson’s disease.
Schizophrenia, bipolar disorder, and other mental illnesses.
As a neuroscientist, I think the most interesting beneficial aspects of being in ketosis are the cognitive benefits. Research supports an overall improvement in things like short-term memory, verbal memory, and mood.
Ketones have neuroprotective properties that protect brain cells. They provide a clean source of energy that burns, increases antioxidants, and reduces inflammation.
– Bryan Barksdale
It is interesting to note that the cause of many mental illnesses is not in the brain: it is in the intestines. Cereal-based diets that are high in carbohydrates can lead to poor gut health; overuse of antibiotics; over the counter drugs; and even the intestinal health of his mother when he was born. Low-fat, high-fat, and ketogenic diets can help improve your mental health by stabilizing your brain chemistry through gut changes.
Researchers suspected a possible link between gluten, the substance found in grains, and schizophrenia in WWII, when grains were rationed, they noted there were fewer hospitalizations . In 1965, an uncontrolled clinical study showed that a ketogenic diet could reduce the symptoms of schizophrenia.
A new case study published in the journal Nutrition & Metabolism (February 26, 2009) published by its researcher, Dr. Eric Westman, found that schizophrenic symptoms resolved after starting a ketogenic diet for weight loss. There are also two other case studies showing that bipolar disorder improves the ketogenic diet as well.
Due to my interest in neuroscience, I am amazed at the ability of a ketogenic diet to improve brain function. This is not only true for people with obvious brain disorders, but it also works for those who are relatively healthy. In this complex world full of daily stress, putting your feet on the ground in terms of brain function can improve your life in many ways. On the other hand, if you want to guarantee a decrease in brain function, I recommend following the standard American diet!
– Dr. Bill Wilson
When Hollywood actress Catherine Zeta-Jones again consulted herself in a clinic to treat her bipolar II disorder in 2011 and 2013, she shed light on this very serious mental condition.
Episodes of depression and mania are characteristic of bipolar disorder (bipolar I disorder tends to be much more obvious in mania, whereas bipolar II disorder can be milder in nature, but still life-changing).
The main treatment is usually the same as the anti-seizure drugs used to treat epilepsy.
As you learned in the previous article, a ketogenic diet was used to treat epileptic seizures. Can A Moderate, Low-Carb, High-Fat Eating Approach Also Contribute To Bipolar Disorder? The answer to that question is not as definitive as you might expect.
Feeding the brain ketones instead of glucose in the body should, in theory, reduce neurotransmitter activity and help stabilize mood.
But in an Israeli case published in the February 2002 issue of the medical journal Bipolar Disorders, a bipolar patient who did not respond to medication was on a ketogenic diet for months.
Doctors added MCT oil to the diet to help boost ketone production. But the patient saw no improvement.
Recent science shows how ketone bodies provide better care, less anxiety, and improve overall mental health.
– Maria Emmerich
This doesn’t really prove that a ketogenic diet doesn’t contribute to bipolar disorder, and there are plenty of anecdotal successes on the internet.
More significantly, in a case study published in the October 2013 issue of Neurocase, two women with bipolar disorder who were in ketosis for more than two years saw better stabilization of mood than tolerated with medication and tolerated. diet changes very well as a bona fide way of life, with no significant adverse effects.
Given the conflicting results of previous case studies, a randomized controlled trial is needed to study the effects of ketogenic diets on schizophrenia, bipolar disorder, and other mental illnesses.
Narcolepsy and other sleep disorders.
Concerns about the human brain’s need for carbohydrates are unfounded. If you stop consuming all the carbohydrates in your diet, you will surely survive, as well as progress, even if you have to undergo a metabolic conversion for fatty acid oxidation for a few weeks, as it can cause temporary fatigue.
– Dr. William Davis
Narcolepsy is a serious neurological disease that causes excessive daytime sleepiness and “sleep attacks.” Medications can help with some sleep-related narcolepsy problems, but they can become more effective over time. In a clinical study published in the June 2004 issue of the medical journal Neurology, nine patients with narcolepsy received low-fat, high-fat ketogenic ketogenic diets for eight weeks.
One patient was unable to complete the study, but the rest experienced less daytime sleepiness, fewer sleep attacks, and saw other improvements in the severity of narcolepsy. The researchers concluded that all of these improvements were likely to have lower glucose levels while the study participants were in ketosis.
Most people with ketosis say they sleep better and don’t feel tired after meals. For those with narcolepsy, it is very necessary to rest in the living hell of their situation. Melissa, one of my blog readers, had narcolepsy before discovering the benefit of keto diet. He practiced narcolepsy since childhood and slept most of the time as a child.
Melisa used a variety of distraction techniques to keep her awake, but most didn’t help. Until she was forty, doctors diagnosed Melisa with narcolepsy.
After trying the best medications to treat it, she found out about the ketogenic diet and decided to leave whole grain carbohydrates, sugar, and starch in her diet to eat more saturated fat to make more ketones in her body.
The results were amazing. Melisa described it as “she was alive again”. Today still eating well, which will help to keep you awake when you need it during the day . Of course, Melissa’s story is simply anecdotal, but she emphasizes that she is doing more rigorous research to find out how low-fat and high-fat ketogenic diets can help people with sleep disorders.
The United States Agency for Defense Advanced Research Projects (DARPA) has been investigating ketosis as a secret weapon for improving the mental and physical performance of soldiers on the battlefield. Why?
When a soldier’s blood glucose drops, he gets confused and sometimes friendly fire is created. So they tested a highly ketogenic fuel source in rats and found that it improved physical and mental performance: the rats were much healthier, lost body fat, had lower levels of triglycerides (fatty acids) in the blood, and lower levels of sugar. in blood. with zero side effects. This same fuel is being developed for soldiers.
– Ben Greenfield
Clearly, physical exercise is not a disease, but it is included here because exciting things are happening for athletes on a keto, low carb, medium protein, high fat, and keto diet. Dr. Stephen Phinney, a ketogenic diet researcher mentioned many times throughout this book, was one of the first to study the effect of ketosis on exercise in 1983.
Their landmark research, published in the journal Metabolism in August 1983, examined how a ketogenic diet affected the endurance training of five elite cyclists.
After eating keto for four weeks on a diet of less than 20 grams of carbohydrates a day, the athletes did not see their performance at risk due to being in ketosis because they switched from sugar burners to fat burners.
Although glycogen stores were considerably lower than baseline at the end of four weeks, not only were they affected by hypoglycemia, but their overall production improved. Then Dr. Phinney coined the phrase nutritional ketosis to describe the condition in which a person is keto-adapted. In the case of these elite athletes, the fuel source has completely changed from carbohydrates (glucose) to fats and ketones.
Using ketosis strategically has been the only way I’ve done it without much effort, and that’s true for my clients as well. For athletes, maintaining or even increasing performance is the only method available to lose an extreme amount of body fat.
– John Kiefer
The 1983 exam ended almost early. The cyclists’ response to the first two weeks of the diet decreased performance, and the researchers thought the nutritional changes were more harmful than helpful. Dr. Phinney happily decided to continue for at least one more week.
It was then that the ketogenic adaptation occurred and improvements began to appear in important data such as oxygen utilization (VO2 max), respiratory rate, the amount of glycogen in the muscle, etc.
Can you imagine how this exam would have turned out if they had stopped after just two weeks? Dr. Phinney cautioned about the importance of this adaptation period on August 27, 2004, in an article titled “Ketogenic Diet and Fitness Performance,” published in the journal Nutrition & Metabolism. You can give the title of this article to Google to read for yourself; it is a complement to everything we have shared with you in this book.
In addition, Dr. Phinney, along with Dr. Jeff Volek, wrote a book in 2012 that explains much more about this information and what they have learned, using a high-fat, high-fat approach with athletes called The Art and the Bass science. Carbohydrate performance.
Although research on athletics and ketogenic diets is still emerging (another study of elite gymnasts was published in the Journal of the International Society of Sports Nutrition in 2012), many elite athletes are willing and openly tested with great success.
One such endurance athlete is Timothy Allen Olson, a long-distance runner from Oregon who competed in the 2012 Western States 100-mile endurance race to show the world what a keto runner could do. Did you win the race?
He bet, and his time was twenty-one minutes faster than the previous course’s record! Ben Greenfield is a triathlete who followed a strict ketogenic diet for sixteen weeks at the Ironman Canada and Ironman Hawaii races. Ironman consumed far fewer carbohydrates than typical triathletes (less than 200 grams). 800 grams of carbohydrates in a workout per day, and is composed of coconut oil and MCT oil, to help your body use fat for fuel.
These are the main benefit of keto diet – Greenfield:
>> Greater metabolic efficiency and better fat burning, which is improved “as the day progresses”. This is especially useful for endurance athletes, such as those who participate in Ironman competitions and long-distance marathons.
>> Decreased glycogen stores, which also leads to increased endurance . It uses less stored liver and muscle carbohydrates because it is able to burn fat more efficiently.
>> Decreased inflammation, allowing the body to recover faster after a workout because free radicals and reactive oxygen species (molecules that can damage cells) are reduced due to high amounts of sugar.
>> More stable energy levels , because blood sugar levels do not change as on a carbohydrate-based diet.
Ketone bodies are known as surplus fuel because they provide more energy than other metabolic fuels per unit of oxygen. This improved metabolic efficiency first appeared in sperm, as exposure to ketones reduced oxygen consumption and increased mobility.
This was later confirmed by the fact that ketone bodies showed an increase in the hydraulic working capacity of the heart and at the same time reduced oxygen consumption. This may explain why the thriving community of zeto-adapted athletes is growing rapidly.
– Dr. Bill Lagakos
Finally, Olaf Sorenson, a forty-year-old runner who is testing the same idea of entering ketosis for athletic performance.
At the time of this writing, you are repeatedly documenting your high fat and fat experience in the movie Two Forty, Forty One, referring to your goal of completing the marathon in less than two hours, forty minutes, and forty seconds. Why is it so important this time?
In 1952, Sorenson’s grandfather qualified for the Olympics around that time.
Now, while trying to equalize ketosis, eat healthy saturated fats and ditch carbs. The University of Florida University for Health and Human Performance is monitoring the progress and health status of your marathon training.
We have very good evidence in favor of ketogenic diets, which can certainly be used in more extensive human clinical research in the years to come.
There are many more conditions that can be improved with low-fat and high-fat diets, but the evidence is less clear: we only have animal models or anecdotal stories in favor of the theory. The therapeutic use of ketones for these conditions is a new area of research that should be studied much more in the coming years, and in the next article we will examine these health conditions.
We have good evidence, from less than a year of research, that a ketogenic diet improves many conditions.
Alzheimer’s, Parkinson’s, and dementia tend to improve on a low-carbohydrate, medium-protein, and high-fat diet.
Schizophrenia, bipolar disorder, and other mental illnesses improve with ketones.
Narcolepsy and other sleep disorders show little improvement in people with ketosis.
Better exercise performance is a great advantage of following a low-carbohydrate, high-fat diet.
I hope this post has given you some great ideas on the benefit of keto diet.